One-Pot Cajun Chicken Alfredo

Featured in: One-Pot Wonders

This one-pot meal features tender chicken simmered with al dente orzo in a velvety Cajun Alfredo sauce. The dish balances smoky paprika and Cajun spices for bold flavor, complemented by garlic, onion, and Parmesan cheese that create a rich, creamy base. Ready in just 30 minutes, it’s perfect for weeknights when you want satisfying comfort with minimal effort. Garnished with fresh parsley, it offers a flavorful, hearty dinner that can be easily adapted with shrimp or sausage. Serve alongside crusty bread or a fresh salad for a complete experience.

Updated on Sun, 23 Nov 2025 13:11:00 GMT
Creamy One-Pot Cajun Chicken Alfredo Orzo, with tender chicken and flavorful sauce, is ready in minutes! Pin
Creamy One-Pot Cajun Chicken Alfredo Orzo, with tender chicken and flavorful sauce, is ready in minutes! | potfuljoy.com

A quick and creamy one-pot meal that blends tender chicken, al dente orzo, and a zesty Cajun Alfredo sauce. Perfect for busy weeknights, this dish delivers bold flavors and comforting richness in just 30 minutes.

This recipe became a family favorite during busy weeknights because it combines simplicity and rich taste in one dish.

Ingredients

  • For the Chicken: 1 lb (450 g) chicken breast, diced (substitute with shrimp or Andouille sausage if desired) Salt and black pepper, to taste
  • For the Spice Blend: 1 tbsp Cajun seasoning (adjust for spice preference) 1 tsp smoked paprika (regular paprika can be used) 1/4 tsp red pepper flakes (optional, for extra heat)
  • For the Base: 2 tbsp olive oil 2 tbsp butter 1 medium onion, chopped (yellow or sweet preferred) 3 cloves garlic, minced
  • For the Pasta: 1 cup (190 g) orzo pasta (substitute with other small pasta if needed)
  • For the Sauce: 2 cups (480 ml) low-sodium chicken broth 1 cup (240 ml) heavy cream (or half and half for a lighter version) 1 cup (90 g) Parmesan cheese, freshly grated
  • For the Garnish: 1 tbsp fresh parsley, chopped

Instructions

Step 1:
Heat olive oil and butter in a large skillet over medium-high heat. Add diced chicken, season with salt and pepper, and sear for 34 minutes until golden brown. Remove chicken and set aside.
Step 2:
In the same skillet, add chopped onion and saute for 23 minutes until translucent. Stir in minced garlic and cook for 1 minute until fragrant.
Step 3:
Add orzo pasta to the skillet, stirring to combine. Toast for 12 minutes until lightly golden.
Step 4:
Pour in chicken broth and sprinkle in Cajun seasoning, smoked paprika, and red pepper flakes. Stir well, bring to a boil, then reduce heat to low. Cover and simmer for 1012 minutes, stirring occasionally, until orzo is al dente and most of the liquid is absorbed.
Step 5:
Remove skillet from heat. Gradually stir in heavy cream and Parmesan cheese until the sauce is creamy and smooth.
Step 6:
Return the cooked chicken to the skillet and stir to combine. Heat through for 1 minute. Taste and adjust seasoning as needed.
Step 7:
Garnish with fresh parsley before serving.
Pin
| potfuljoy.com

Making this dish always brings the family together around the dinner table for a cozy meal.

Notes

For extra veggies, add bell peppers or spinach. Serve with crusty bread or a green salad and pair with chilled Sauvignon Blanc or light lager.

Required Tools

Large skillet with lid, wooden spoon or spatula, chefs knife, cutting board, measuring cups and spoons, grater for Parmesan.

Allergen Information

Contains dairy (butter, cream, Parmesan cheese) and gluten (orzo pasta). May contain traces of other allergens always check ingredient labels if sensitivity is a concern.

A close-up view of the rich, one-pot Cajun Chicken Alfredo Orzo, garnished with fresh parsley. Pin
A close-up view of the rich, one-pot Cajun Chicken Alfredo Orzo, garnished with fresh parsley. | potfuljoy.com

Enjoy a rich and flavorful meal that’s ready in just 30 minutes.

Recipe Q&A

Can I substitute the chicken with seafood?

Yes, shrimp works well as a substitute and should be cooked until just opaque. Adjust cooking time accordingly.

What can I use instead of orzo pasta?

Small pasta shapes like acini di pepe or small shells make great alternatives if orzo is unavailable.

How spicy is the Cajun seasoning in this dish?

The spice level can be adjusted by varying the amount of Cajun seasoning and red pepper flakes to suit your preference.

Can I make this dish lighter?

Using half and half instead of heavy cream and reducing Parmesan cheese will result in a lighter, less rich sauce.

What sides pair well with this dish?

Crusty bread, a green salad, or steamed vegetables complement the creamy and spicy flavors nicely.

Is it possible to add vegetables to the dish?

Yes, bell peppers or fresh spinach can be added for extra color and nutrients without altering the cooking process significantly.

One-Pot Cajun Chicken Alfredo

Creamy Cajun chicken and orzo combine in a zesty, one-pot meal full of bold flavor and easy prep.

Preparation time
10 min
Cooking time
20 min
Total time
30 min

Category One-Pot Wonders

Difficulty Easy

Origin Cajun

Yield 4 Servings

Dietary specifications None specified

Ingredients

Chicken

01 1 lb diced chicken breast
02 Salt and black pepper to taste

Spice Blend

01 1 tbsp Cajun seasoning
02 1 tsp smoked paprika
03 1/4 tsp red pepper flakes (optional)

Base

01 2 tbsp olive oil
02 2 tbsp butter
03 1 medium onion, chopped
04 3 cloves garlic, minced

Pasta

01 1 cup orzo pasta

Sauce

01 2 cups low-sodium chicken broth
02 1 cup heavy cream
03 1 cup freshly grated Parmesan cheese

Garnish

01 1 tbsp fresh parsley, chopped

Instructions

Step 01

Sear Chicken: Heat olive oil and butter in a large skillet over medium-high heat. Season diced chicken with salt and black pepper, then sear for 3 to 4 minutes until golden brown. Remove and set aside.

Step 02

Sauté Aromatics: In the same skillet, add chopped onion and cook for 2 to 3 minutes until translucent. Stir in minced garlic and cook for an additional 1 minute until fragrant.

Step 03

Toast Orzo: Add orzo pasta to the skillet, stirring continuously to coat and toast for 1 to 2 minutes until lightly golden.

Step 04

Simmer Pasta: Pour in chicken broth and add Cajun seasoning, smoked paprika, and red pepper flakes. Stir well, bring to a boil, then reduce heat to low. Cover and simmer for 10 to 12 minutes, stirring occasionally, until orzo is al dente and most liquid is absorbed.

Step 05

Incorporate Cream and Cheese: Remove skillet from heat. Gradually stir in heavy cream and Parmesan cheese until the sauce becomes creamy and smooth.

Step 06

Combine Chicken and Finish: Return cooked chicken to the skillet, stirring to combine thoroughly. Heat through for 1 minute, then adjust seasoning to taste.

Step 07

Garnish and Serve: Sprinkle chopped fresh parsley over the dish before serving.

Required equipment

  • Large skillet with lid
  • Wooden spoon or spatula
  • Chef's knife
  • Cutting board
  • Measuring cups and spoons
  • Grater for Parmesan cheese

Allergen information

Review each ingredient to identify potential allergens and if uncertain, please consult a healthcare professional.
  • Contains dairy: butter, cream, Parmesan cheese
  • Contains gluten: orzo pasta

Nutritional values (per serving)

These values are provided as a general guide only and shouldn't replace professional medical advice.
  • Calories: 560
  • Fat: 28 g
  • Carbs: 45 g
  • Protein: 35 g