One-Pot Cajun Chicken Alfredo

Featured in: One-Pot Wonders

This dish combines tender chicken pieces with smoky Cajun spices and a rich Alfredo sauce, all cooked together with orzo pasta in a single pot. Sautéed onion, garlic, and red bell pepper add depth and sweetness while baby spinach and Parmesan cheese enrich the creamy texture. The orzo absorbs the flavorful broth, creating a comforting and quick meal ideal for busy weeknights. Garnished with fresh parsley and extra cheese, it’s a flavorful and satisfying entrée with a balance of spice and creaminess.

Updated on Sun, 23 Nov 2025 10:07:00 GMT
Golden-brown chicken pieces mingle with creamy sauce in this One-Pot Cajun Chicken Alfredo Orzo. Pin
Golden-brown chicken pieces mingle with creamy sauce in this One-Pot Cajun Chicken Alfredo Orzo. | potfuljoy.com

A creamy, spicy, and comforting one-pot meal combining tender chicken, smoky Cajun spices, velvety Alfredo sauce, and orzo pasta for a quick weeknight dinner.

This dish quickly became one of my favorites for busy evenings because it combines bold flavors and minimal cleanup.

Ingredients

  • Proteins: 2 large boneless skinless chicken breasts (about 450 g) cut into bite sized pieces
  • Vegetables: 1 small yellow onion finely chopped, 3 cloves garlic minced, 1 red bell pepper diced, 1 cup baby spinach roughly chopped (optional)
  • Pantry: 2 tablespoons olive oil, 1 1/2 cups (300 g) orzo pasta, 2 1/2 cups (600 ml) low sodium chicken broth, 1 cup (240 ml) heavy cream, 1/2 cup (120 ml) milk
  • Spices & Seasonings: 1 tablespoon Cajun seasoning (store bought or homemade), 1/2 teaspoon smoked paprika, 1/2 teaspoon salt or to taste, 1/4 teaspoon freshly ground black pepper, Pinch of cayenne pepper (optional for extra heat)
  • Cheeses: 3/4 cup (75 g) freshly grated Parmesan cheese
  • Garnish: Chopped fresh parsley, Extra Parmesan cheese

Instructions

Step 1:
Season the chicken pieces with half of the Cajun seasoning salt and pepper.
Step 2:
In a large deep skillet or Dutch oven heat olive oil over medium high heat. Add the chicken and sauté until browned and just cooked through about 5 6 minutes. Remove chicken to a plate and set aside.
Step 3:
In the same pot add onion and bell pepper. Sauté for 3 minutes until softened. Add garlic and cook for 1 minute more.
Step 4:
Stir in the orzo smoked paprika remaining Cajun seasoning and cayenne pepper. Toast the orzo for 1 minute stirring frequently.
Step 5:
Pour in the chicken broth heavy cream and milk. Stir well scraping any browned bits from the bottom.
Step 6:
Bring to a gentle boil then reduce heat to medium low. Cover and simmer for 10 12 minutes stirring occasionally until orzo is tender and most liquid is absorbed.
Step 7:
Return the chicken to the pot along with spinach (if using). Stir in Parmesan cheese until melted and creamy.
Step 8:
Taste and adjust seasoning. If sauce is too thick add a splash more milk or broth.
Step 9:
Serve hot garnished with parsley and extra Parmesan.
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| potfuljoy.com

This recipe always brings my family together after a long day with its comforting flavors and easy prep.

Notes

Add mushrooms or peas for extra vegetables. Serve with crusty bread or a green salad.

Required Tools

Large deep skillet or Dutch oven with lid, Cutting board and knife, Wooden spoon or spatula, Measuring cups and spoons, Grater (for Parmesan)

Allergen Information

Contains Dairy (cream milk Parmesan) Wheat (orzo) Possible Celery (in broth). Check Cajun seasoning and broth labels for hidden allergens.

A steaming bowl of One-Pot Cajun Chicken Alfredo Orzo, garnished with fresh parsley, awaits your fork. Pin
A steaming bowl of One-Pot Cajun Chicken Alfredo Orzo, garnished with fresh parsley, awaits your fork. | potfuljoy.com

Serve this dish immediately for the best creamy texture and savor the rich Cajun flavors in every bite.

Recipe Q&A

Can I substitute chicken with other proteins?

Yes, shrimp or smoked sausage can be used instead of chicken to create different flavor profiles.

Is it necessary to use fresh Parmesan cheese?

Freshly grated Parmesan melts better and adds a richer flavor, enhancing the creamy sauce texture.

How can I adjust the heat level in this dish?

Adjust cayenne pepper or Cajun seasoning amounts to increase or reduce spiciness according to preference.

Can I use a different type of pasta instead of orzo?

Small pasta shapes like acini di pepe or couscous can substitute for orzo for similar texture and cooking times.

What can I do if the sauce becomes too thick?

Add a splash of milk or chicken broth gradually until desired sauce consistency is reached.

One-Pot Cajun Chicken Alfredo

Creamy, spicy chicken with Cajun seasoning, Alfredo sauce, and orzo pasta cooked all in one pot.

Preparation time
15 min
Cooking time
25 min
Total time
40 min

Category One-Pot Wonders

Difficulty Easy

Origin American, Cajun-Inspired

Yield 4 Servings

Dietary specifications None specified

Ingredients

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces (about 16 oz)

Vegetables

01 1 small yellow onion, finely chopped
02 3 cloves garlic, minced
03 1 red bell pepper, diced
04 1 cup baby spinach, roughly chopped (optional)

Pantry

01 2 tablespoons olive oil
02 1 1/2 cups orzo pasta (10.5 oz)
03 2 1/2 cups low-sodium chicken broth (20 fl oz)
04 1 cup heavy cream (8 fl oz)
05 1/2 cup milk (4 fl oz)

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 1/2 teaspoon smoked paprika
03 1/2 teaspoon salt, or to taste
04 1/4 teaspoon freshly ground black pepper
05 Pinch of cayenne pepper (optional)

Cheeses

01 3/4 cup freshly grated Parmesan cheese (2.5 oz)

Garnish

01 Chopped fresh parsley
02 Extra Parmesan cheese

Instructions

Step 01

Season chicken: Combine chicken pieces with half of the Cajun seasoning, salt, and black pepper.

Step 02

Brown chicken: Heat olive oil in a large deep skillet or Dutch oven over medium-high heat. Add chicken and sauté 5 to 6 minutes until browned and just cooked through. Remove chicken and set aside.

Step 03

Sauté vegetables: In the same pot, add onion and red bell pepper; cook for 3 minutes until softened. Add garlic and sauté 1 additional minute.

Step 04

Toast orzo and spices: Stir in orzo, smoked paprika, remaining Cajun seasoning, and cayenne pepper. Toast for 1 minute, stirring frequently.

Step 05

Add liquids and simmer: Pour in chicken broth, heavy cream, and milk. Stir thoroughly, scraping browned bits from the bottom. Bring to a gentle boil, then reduce heat to medium-low, cover, and simmer 10 to 12 minutes, stirring occasionally, until orzo is tender and liquid mostly absorbed.

Step 06

Incorporate chicken and spinach: Return chicken to the pot and add spinach if using. Stir in Parmesan cheese until melted and creamy.

Step 07

Adjust seasoning and serve: Taste and adjust seasoning. If sauce is too thick, add a splash of milk or broth. Serve hot, garnished with fresh parsley and extra Parmesan.

Required equipment

  • Large deep skillet or Dutch oven with lid
  • Cutting board and knife
  • Wooden spoon or spatula
  • Measuring cups and spoons
  • Grater for Parmesan cheese

Allergen information

Review each ingredient to identify potential allergens and if uncertain, please consult a healthcare professional.
  • Contains dairy (cream, milk, Parmesan) and wheat (orzo pasta)
  • May contain celery in broth or seasoning blends

Nutritional values (per serving)

These values are provided as a general guide only and shouldn't replace professional medical advice.
  • Calories: 570
  • Fat: 27 g
  • Carbs: 48 g
  • Protein: 37 g